Targeting TEAD Hydrophobic Pocket for Cancer Therapy or Regenerative Medicine

Time: 4:00 pm
day: Day One


  • TEAD transcriptional factors are downstream effectors of Hippo pathway
  • We discovered that TEADs have a druggable hydrophobic pocket
  • We identified several chemical compounds targeting the TEAD hydrophobic pocket
  • Targeting TEADs represents a novel revenue for drug development