YAP-dependent proliferation by a small molecule for regenerative repair

Time: 3:30 pm
day: Day Two


  • Pharmacological activation of YAP through small molecule targeting of a key scaffolding/sensor protein which is contextually essential in relaying inhibitory phosphorylation to YAP.
  • Potential transient or pulsatile dosing of a YAP-activating drug may be beneficial for organ repair in acute clinical settings, such as heart failure or diabetic wounds.